COMPARTMENTS

Subcellular localization database

CCL2 localizations

CCL2 [ENSP00000225831]

C-C motif chemokine 2; Acts as a ligand for C-C chemokine receptor CCR2 . Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions . Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils . May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis . ECO:0000269|PubMed:8107690, ECO:0000269|PubMed:8195247, ECO:0000269|PubMed:8627182, ECO:0000269|PubMed:9792674,

Synonyms:  CCL2,  CCL2p,  hCCL2,  J3KRT7,  P13500 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence