UNC93B1 localizations
UNC93B1 [ENSP00000227471]
Protein unc-93 homolog B1; Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling. Required for the transport of a subset of TLRs (including TLR3, TLR7 and TLR9) from the endoplasmic reticulum to endolysosomes where they can engage pathogen nucleotides and activate signaling cascades. May play a role in autoreactive B-cells removal. ; Belongs to the unc-93 family.
Synonyms: UNC93B1, UNC93B1p, hUNC93B1, E9PNE5, E9PR93 ...