WDFY1 localizations
WDFY1 [ENSP00000233055]
WD repeat and FYVE domain-containing protein 1; Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines .
Synonyms: WDFY1, WDFY1p, hWDFY1, A0A024R488, C9JJ54 ...