COMPARTMENTS

Subcellular localization database

RHBDF1 localizations

RHBDF1 [ENSP00000262316]

Inactive rhomboid protein 1; Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own. ECO:0000269|PubMed:18524845, ECO:0000269|PubMed:18832597,

Synonyms:  RHBDF1,  RHBDF1p,  hRHBDF1,  A0A1B0GXG1,  B8ZZ07 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence