GID8 localizations
GID8 [ENSP00000266069]
Glucose-induced degradation protein 8 homolog; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 . Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation ; Belongs to the GID8 family.
Synonyms: GID8, GID8p, hGID8, Q9NWU2, Q9NWU2p ...