COMPARTMENTS

Subcellular localization database

PRUNE1 localizations

PRUNE1 [ENSP00000271620]

Exopolyphosphatase PRUNE1; Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, migration and differentiation, and acts as a negative regulator of NME1. Plays a role in the regulation of neurogenesis . Involved in the regulation of microtubule polymerization . ECO:0000269|PubMed:14998490, ECO:0000269|PubMed:16428445,

Synonyms:  PRUNE1,  PRUNE1p,  hPRUNE1,  A0A3B3ITN0,  Q5SZF2 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence