COMPARTMENTS

Subcellular localization database

ETAA1 localizations

ETAA1 [ENSP00000272342]

Ewing's tumor-associated antigen 1; Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity . Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1 . Probably only regulates a subset of ATR targets .

Synonyms:  ETAA1,  ETAA1p,  hETAA1,  A0A2R8Y6Y8,  A0A2R8Y7B6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence