DOCK11 localizations
DOCK11 [ENSP00000276202]
Dedicator of cytokinesis protein 11; Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Required for marginal zone (MZ) B-cell development, is associated with early bone marrow B-cell development, MZ B-cell formation, MZ B-cell number and marginal metallophilic macrophages morphology. Facilitates filopodia formation through the activation of CDC42; Belongs to the DOCK family.
Synonyms: DOCK11, DOCK11p, hDOCK11, A0A0J9YW64, A0A0J9YXQ7 ...