DOCK5 localizations
DOCK5 [ENSP00000276440]
Dedicator of cytokinesis protein 5; Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP (By similarity). Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen .
Synonyms: DOCK5, DOCK5p, hDOCK5, B9A015, H0Y7N4 ...