COMPARTMENTS

Subcellular localization database

USP12 localizations

USP12 [ENSP00000282344]

Ubiquitin carboxyl-terminal hydrolase 12; Deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with WDR20 and WDR48 to have a high activity . Not involved in deubiquitination of monoubiquitinated FANCD2 . In complex with WDR48, acts as a potential tumor suppressor by positively regulating PHLPP1 stability . ; Belongs to the peptidase C19 family. USP12/USP46 subfamily.

Synonyms:  USP12,  USP12p,  hUSP12,  A0A087WUU2,  A0A087WWP2 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence