FGD5 localizations
FGD5 [ENSP00000285046]
FYVE, RhoGEF and PH domain-containing protein 5; Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF- induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape.
Synonyms: FGD5, FGD5p, hFGD5, A0A1W2PRG7, A0A2X0SFF2 ...