COMPARTMENTS

Subcellular localization database

SHKBP1 localizations

SHKBP1 [ENSP00000291842]

SH3KBP1-binding protein 1; Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation. ; Belongs to the KCTD3 family.

Synonyms:  SHKBP1,  SHKBP1p,  hSHKBP1,  M0QX42,  M0QXA4 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence