KCNIP3 localizations
KCNIP3 [ENSP00000295225]
Calsenilin; Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception (By similarity). May play a role in the regulation of PSEN2 proteolytic processing and apoptosis. Together with PSEN2 involved in modulation of amyloid-beta formation.
Synonyms: KCNIP3, KCNIP3p, hKCNIP3, A0A024RE22, A0A0A0MRH3 ...
Linkouts: STRING Pharos UniProt OMIM
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