COMPARTMENTS

Subcellular localization database

HELQ localizations

HELQ [ENSP00000295488]

Helicase POLQ-like; Single-stranded DNA-dependent ATPase and 5' to 3' DNA helicase . Involved in the repair of DNA cross-links and double-strand break (DSB) resistance. Participates in FANCD2- mediated repair. Forms a complex with POLN polymerase that participates in homologous recombination (HR) repair and is essential for cellular protection against DNA cross-links . ; Belongs to the helicase family. SKI2 subfamily.

Synonyms:  HELQ,  E3W980,  E3W982,  Q8TDG4,  E3W980p ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence