MAD2L1 localizations
MAD2L1 [ENSP00000296509]
Mitotic spindle assembly checkpoint protein MAD2A; Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.
Synonyms: MAD2L1, MAD2L1p, hMAD2L1, D6RJE3, Q13257 ...