SAP30L localizations
SAP30L [ENSP00000297109]
Histone deacetylase complex subunit SAP30L; [Isoform 1]: Functions as transcription repressor, probably via its interaction with histone deacetylase complexes . Involved in the functional recruitment of the class 1 Sin3-histone deacetylase complex (HDAC) to the nucleolus . Binds DNA, apparently without sequence-specificity, and bends bound double-stranded DNA . Binds phosphoinositol phosphates (phosphoinositol 3- phosphate, phosphoinositol 4-phosphate and phosphoinositol 5-phosphate) via the same basic sequence motif that mediates DNA binding and nuclear import . [Isoform 3]: Functions as transcription repressor; its activity is marginally lower than that of isoform 1. ; Belongs to the SAP30 family.
Synonyms: SAP30L, SAP30Lp, hSAP30L, Q9HAJ7, Q9HAJ7p ...