DEUP1 localizations
DEUP1 [ENSP00000298050]
Deuterosome assembly protein 1; Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis (By similarity); Belongs to the CEP63 family.
Synonyms: DEUP1, DEUP1p, hDEUP1, A0A087WVI3, A0A088AWP1 ...