COMPARTMENTS

Subcellular localization database

RNASE7 localizations

RNASE7 [ENSP00000298690]

Ribonuclease 7; Exhibits a potent RNase activity (PubMed:12244054, PubMed:12527768, PubMed:17150966). Has broad-spectrum antimicrobial activity against many pathogenic microorganisms and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium (PubMed:12244054, PubMed:12527768, PubMed:25075772, PubMed:17150966). Causes loss of bacterial membrane integrity . Probably contributes to urinary tract sterility . Bactericidal activity is independent of RNase activity . ECO:0000269|PubMed:12527768, ECO:0000269|PubMed:17150966,; Belongs to the pancreatic ribonuclease family.

Synonyms:  RNASE7,  RNASE7p,  hRNASE7,  Q9H1E1,  Q9H1E1p ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence