TMIGD2 localizations
TMIGD2 [ENSP00000301272]
Transmembrane and immunoglobulin domain-containing protein 2; Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
Synonyms: TMIGD2, TMIGD2p, hTMIGD2, A0A0B4J2A9, A0A0B4J2B0 ...