RETREG1 localizations
RETREG1 [ENSP00000304642]
Reticulophagy regulator 1; Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes . Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins . Required for long-term survival of nociceptive and autonomic ganglion neurons .
Synonyms: RETREG1, RETREG1p, hRETREG1, H0Y9U4, Q9H6L5 ...