COMPARTMENTS

Subcellular localization database

ESCO2 localizations

ESCO2 [ENSP00000306999]

N-acetyltransferase ESCO2; Acetyltransferase required for the establishment of sister chromatid cohesion . Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during the S phase. Acetylates the cohesin component SMC3 . ECO:0000269|PubMed:15958495, ECO:0000269|PubMed:19907496,

Synonyms:  ESCO2,  ESCO2p,  hESCO2,  E5RFE4,  E5RFP7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence