RESF1 localizations
RESF1 [ENSP00000310338]
Retroelement silencing factor 1; Plays a role in the regulation of imprinted gene expression, regulates repressive epigenetic modifications associated with SETDB1. Required for the recruitment or accumulation of SETDB1 to the endogenous retroviruses (ERVs) and maintenance of repressive chromatin configuration, contributing to a subset of the SETDB1-dependent ERV silencing in embryonic stem cells.
Synonyms: RESF1, RESF1p, hRESF1, F5H488, J3KPI3 ...