COMPARTMENTS

Subcellular localization database

PPP1R8 localizations

PPP1R8 [ENSP00000311677]

Nuclear inhibitor of protein phosphatase 1; Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre- mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation.

Synonyms:  PPP1R8,  PPP1R8p,  hPPP1R8,  A0A0A0MT09,  Q12972 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence