COMPARTMENTS

Subcellular localization database

CRMP1 localizations

CRMP1 [ENSP00000321606]

Dihydropyrimidinase-related protein 1; Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton . Plays a role in axon guidance . During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone . Involved in invasive growth and cell migration . May participate in cytokinesis .

Synonyms:  CRMP1,  CRMP1p,  hCRMP1,  E9PD68,  Q14194 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence