YAF2 localizations
YAF2 [ENSP00000328004]
YY1-associated factor 2; Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the E2F6.com-1 complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in chromatin-remodeling.
Synonyms: YAF2, YAF2p, hYAF2, A0A0B4J255, F8VRE5 ...