KNTC1 localizations
KNTC1 [ENSP00000328236]
Kinetochore-associated protein 1; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores . Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
Synonyms: KNTC1, KNTC1p, hKNTC1, E7ES84, F5H5V0 ...