IZUMO1R localizations
IZUMO1R [ENSP00000332963]
Sperm-egg fusion protein Juno; Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate.
Synonyms: IZUMO1R, IZUMO1Rp, hIZUMO1R, A6ND01, J3KNP7 ...