NFAM1 localizations
NFAM1 [ENSP00000333680]
NFAT activation molecule 1; May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking.
Synonyms: NFAM1, NFAM1p, hNFAM1, F8WE95, Q8NET5 ...