ARHGAP10 localizations
ARHGAP10 [ENSP00000336923]
Rho GTPase-activating protein 10; GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).
Synonyms: ARHGAP10, A0A2X0SFB3, A1A4S6, H0Y8W5, A1A4S6p ...