USP1 localizations
USP1 [ENSP00000343526]
Ubiquitin carboxyl-terminal hydrolase 1; Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2 . Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA . Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity .
Synonyms: USP1, USP1p, hUSP1, C9JC88, C9JWX4 ...