COMPARTMENTS

Subcellular localization database

NUP50 localizations

NUP50 [ENSP00000345895]

Nuclear pore complex protein Nup50; Component of the nuclear pore complex that has a direct role in nuclear protein import . Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin- alpha:beta-cargo complex and importin recycling . Interacts with regulatory proteins of cell cycle progression including CDKN1B (By similarity). This interaction is required for correct intracellular transport and degradation of CDKN1B (By similarity).

Synonyms:  NUP50,  NUP50p,  hNUP50,  A0A024R4X7,  A0A0G2JI20 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence