MAFG localizations
MAFG [ENSP00000350369]
Transcription factor MafG; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves . However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2, NFE2L1 and NFE2L2, and recruiting them to specific DNA-binding sites (PubMed:8932385, PubMed:9421508, PubMed:11154691). Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NFE2L2 transcription factor . Transcription factor, component of erythroid- specific transcription factor NFE2L2 . Activates globin gene expression when associated with NFE2L2 . May be involved in signal transduction of extracellular H(+) (By similarity). ECO:0000269|PubMed:11154691, ECO:0000269|PubMed:8932385,
Synonyms: MAFG, A0A024R8X1, I3L2F8, O15525, I3L2F8p ...