COMPARTMENTS

Subcellular localization database

SPOUT1 localizations

SPOUT1 [ENSP00000354812]

Putative methyltransferase C9orf114; Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase (PubMed:20813266, PubMed:25657325). Also involved in chromosome alignment . May promote centrosome maturation probably by recruiting A-kinase anchor protein AKAP9 to centrosomes in early mitosis . Binds specifically to miRNA MIR145 hairpin, regulates MIR145 expression at a postranscriptional level .

Synonyms:  SPOUT1,  SPOUT1p,  hSPOUT1,  Q5T280,  R4GNG4 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence