SDCCAG8 localizations
SDCCAG8 [ENSP00000355499]
Serologically defined colon cancer antigen 8; Plays a role in the establishment of cell polarity and epithelial lumen formation (By similarity). Plays also an essential role in ciliogenesis and subsequent Hedgehog signaling pathway that requires the presence of intact primary cilia for pathway activation. Mechanistically, interacts with and mediates RABEP2 centrosomal localization which is critical for ciliogenesis .
Synonyms: SDCCAG8, SDCCAG8p, hSDCCAG8, A0A0C4DG71, Q86SQ7 ...