COMPARTMENTS

Subcellular localization database

RAB29 localizations

RAB29 [ENSP00000356107]

Ras-related protein Rab-7L1; The small GTPases Rab are key regulators in vesicle trafficking . Essential for maintaining the integrity of the endosome-trans-Golgi network structure (By similarity). Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner . Recruits LRRK2 to the Golgi complex and stimulates LRRK2 kinase activity . Regulates neuronal process morphology in the intact central nervous system (CNS) (By similarity). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection .

Synonyms:  RAB29,  RAB29p,  hRAB29,  E9PL56,  O14966 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence