ASCC3 localizations
ASCC3 [ENSP00000358159]
Activating signal cointegrator 1 complex subunit 3; 3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions . Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation .
Synonyms: ASCC3, ASCC3p, hASCC3, E5RFZ0, J3KNJ4 ...