PTBP2 localizations
PTBP2 [ENSP00000359216]
Polypyrimidine tract-binding protein 2; RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA.
Synonyms: PTBP2, PTBP2p, hPTBP2, Q9UKA9, Q9UKA9p ...