GBP5 localizations
GBP5 [ENSP00000359488]
Guanylate-binding protein 5; As an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents . Hydrolyzes GTP, but in contrast to other family members, does not produce GMP . ; Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily.
Synonyms: GBP5, GBP5p, hGBP5, E7ETN8, Q96PP8 ...