ENDOG localizations
ENDOG [ENSP00000361725]
Endonuclease G, mitochondrial; Cleaves DNA at double-stranded (DG)n.(DC)n and at single- stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA (By similarity); Belongs to the DNA/RNA non-specific endonuclease family.
Synonyms: ENDOG, E5KNL5, Q14249, E5KNL5p, hE5KNL5 ...