CDCA8 localizations
CDCA8 [ENSP00000362146]
Borealin; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.
Synonyms: CDCA8, CDCA8p, hCDCA8, Q53HL2, Q53HL2p ...