XPA localizations
XPA [ENSP00000364270]
DNA repair protein complementing XP-A cells; Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation. ; Belongs to the XPA family.
Synonyms: XPA, F2Z2T2, P23025, F2Z2T2p, hF2Z2T2 ...