COMPARTMENTS

Subcellular localization database

POGLUT2 localizations

POGLUT2 [ENSP00000365172]

Protein O-glucosyltransferase 2; Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C . Can also catalyze the transfer of xylose from UDP-xylose but less efficiently . Specifically targets extracellular EGF repeats of proteins such as NOTCH1 and NOTCH3 . May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway . ; Belongs to the KDELC family.

Synonyms:  POGLUT2,  POGLUT2p,  hPOGLUT2,  Q6UW63,  Q6UW63p ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence