PNLDC1 localizations
PNLDC1 [ENSP00000376007]
Poly(A)-specific ribonuclease PNLDC1; 3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails . Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development . May act as a regulator of multipotency in embryonic stem cells (By similarity).
Synonyms: PNLDC1, PNLDC1p, hPNLDC1, Q8NA58, V9GYA0 ...