COMPARTMENTS

Subcellular localization database

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CASP5 localizations

CASP5 [ENSP00000376849]

Caspase-5 subunit p10; Mediator of programmed cell death (apoptosis). During non- canonical inflammasome activation, cuts CGAS and may play a role in the regulation of antiviral innate immune activation .

Synonyms:  CASP5,  CASP5p,  hCASP5,  C9JF14,  H7C0P5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence

The subcellular localizations are derived from database annotations, automatic text mining of the biomedical literature, and sequence-based predictions. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Janos Binder, Sune Frankild, Kalliopi Tsafou, Christian Stolte, Sean O'Donoghue, Reinhard Schneider, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research (CPR), the Luxembourg Centre for Systems Biomedicine (LCSB), and the Commonwealth Scientific and Industrial Research Organisation (CSIRO).