COMPARTMENTS

Subcellular localization database

RCCD1 localizations

RCCD1 [ENSP00000377801]

RCC1 domain-containing protein 1; Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8 . Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation . Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8 .

Synonyms:  RCCD1,  RCCD1p,  hRCCD1,  A0A024RC72,  A6NED2 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence