RCCD1 localizations
RCCD1 [ENSP00000377801]
RCC1 domain-containing protein 1; Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8 . Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation . Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8 .
Synonyms: RCCD1, RCCD1p, hRCCD1, A0A024RC72, A6NED2 ...