COMPARTMENTS

Subcellular localization database

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FAF1 localizations

FAF1 [ENSP00000379457]

FAS-associated factor 1; Ubiquitin-binding protein . Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation . Potentiates but cannot initiate FAS-induced apoptosis (By similarity).

Synonyms:  FAF1,  FAF1p,  hFAF1,  B1ANM7,  B3KT28 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence

The subcellular localizations are derived from database annotations, automatic text mining of the biomedical literature, and sequence-based predictions. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Janos Binder, Sune Frankild, Kalliopi Tsafou, Christian Stolte, Sean O'Donoghue, Reinhard Schneider, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research (CPR), the Luxembourg Centre for Systems Biomedicine (LCSB), and the Commonwealth Scientific and Industrial Research Organisation (CSIRO).