COMPARTMENTS

Subcellular localization database

OSBPL10 localizations

OSBPL10 [ENSP00000379804]

Oxysterol-binding protein-related protein 10; Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P (Probable). Plays a role in negative regulation of lipid biosynthesis . Negatively regulates APOB secretion from hepatocytes . Binds cholesterol and acidic phospholipids . Also binds 25- hydroxycholesterol . Binds phosphatidylserine . ECO:0000269|PubMed:19554302, ECO:0000269|PubMed:22906437,

Synonyms:  OSBPL10,  OSBPL10p,  hOSBPL10,  H7C199,  H7C487 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence