FGL1 localizations
FGL1 [ENSP00000381133]
Fibrinogen-like protein 1; Immune suppressive molecule that inhibits antigen-specific T- cell activation by acting as a major ligand of LAG3 . Responsible for LAG3 T-cell inhibitory function . Binds LAG3 independently from MHC class II (MHC-II) . Secreted by, and promotes growth of, hepatocytes (PubMed:11470158, PubMed:19880967).
Synonyms: FGL1, FGL1p, hFGL1, Q08830, Q08830p ...