COMPARTMENTS

Subcellular localization database

DOT1L localizations

DOT1L [ENSP00000381657]

Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones . Binds to DNA .

Synonyms:  DOT1L,  DOT1Lp,  hDOT1L,  A0A087X1A7,  C9JH95 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence