DUSP28 localizations
DUSP28 [ENSP00000385885]
Dual specificity phosphatase 28; Has phosphatase activity with the synthetic substrate 6,8- difluoro-4-methylumbelliferyl phosphate (in vitro) (PubMed:24531476, PubMed:29121083). Has almost no detectable activity with phosphotyrosine, even less activity with phosphothreonine and displays complete lack of activity with phosphoserine . The poor activity with phosphotyrosine may be due to steric hindrance by bulky amino acid sidechains that obstruct access to the active site ; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
Synonyms: DUSP28, DUSP28p, hDUSP28, H7C234, Q4G0W2 ...